On September 18 , 2024 , according to Japanese media, Japan’s Ministry of Health, Labor and Welfare stated that Kobayashi Pharmaceutical’s health products containing red yeast rice ingredients had caused damage to consumers’ health, and that it had confirmed that “pilenicillic acid” had been detected in the problematic raw materials. is the cause of damage to health. Penicillic acid is a natural compound produced by Penicillium moldum.

Kobayashi Pharmaceutical Co., Ltd. previously reported to the Ministry of Health, Labor and Welfare that "penicillic acid" was detected in the red yeast raw materials produced by its Osaka factory in September last year.