NMN - an emerging anti-aging star ingredient

NMN, full name "β-nicotinamide mononucleotide", is a naturally occurring biologically active nucleotide, but also an important supplement for NAD+ (nicotinamide adenine dinucleotide), NMN has been proved to increase the level of NAD+ in human cells, which is beneficial for slowing down the aging of the cells, etc. NMN exists in a variety of organisms, such as fruits and vegetables. various organisms, such as fruits and vegetables. At the same time, NMN is also an inherent substance in the human body, which participates in a wide range of biochemical reactions in the body, and is closely related to the human body's immunity and metabolism.

"Anti-aging" is one of the significant properties of NMN. Several studies have shown that NAD+ depletion is closely related to stem cell aging and mitochondrial metabolic disorders. As we age, NAD+ levels in our bodies gradually decline, leading to weakened cellular functions, which in turn leads to a series of aging symptoms, such as muscle deterioration, loss of brain power, deepening of pigmentation, hair loss, and so on. Some experiments have proved that promoting NAD+ levels is considered an effective way to slow down aging, and supplementing NMN can accelerate the increase of NAD+ levels in the body, repairing damaged cells and boosting the body's immunity. In addition to its anti-aging properties, NMN has also been shown to protect the heart, prevent diabetes, Alzheimer's disease, improve metabolism, enhance cardiovascular health and reduce inflammation.

According to business research, the global NMN market will reach USD 356.1 million in 2022 and is expected to reach USD 1,867.77 million by 2031, growing at a CAGR of 20.2% during the forecast period.

NMN products have been widely used abroad

As the content of NMN in most organisms is low, dietary supplementation is also required to increase the level of NMN in the human body. At present, the method of artificially preparing NMN is mainly biosynthesis. Currently, countries that explicitly use NMN as a food ingredient or natural health product component include Japan and Canada.

In Japan, companies that produce and develop NMN health products include Meiji Pharmaceutical Co., Ltd, LEVANTE, ATRITENA, and others. Meiji Pharmaceuticals NMN 10000 Supreme MSNS is a nutraceutical product manufactured by the Japanese pharmaceutical company Meiji Pharmaceutical Co. The product is designed to help promote cellular health and energy metabolism in the body and may produce anti-aging effects. The product detail page describes the product as having over 95% NMN purity.

LEVANTE of Nagoya, Japan, has launched an NMN anti-aging supplement that uses yeast fermentation method and contains ingredients such as NMN, vegetable oil containing vitamin E, red wine extract powder containing resveratrol, coenzyme Q10, echinacea extract (echinacea extract, dextrin), royal jelly, alpha lipoic acid, and aloe vera powder*/cellulose.

In 2021, the Canadian Natural Health Products Database listed NMN as a natural health product ingredient and NMN dietary products can be legally sold in Canada. Canadian brand Prairie Naturals has launched an NMN supplement with key ingredients including NMN, resveratrol and quercetin. The product allows older adults to restore cellular health and prevent age-related diseases.

In China, NMN cannot be produced and operated as food, but it has become an emerging ingredient in the cosmetic field. According to the State Drug Administration data show that, as of May 13, on the NMN new cosmetic raw materials for the record information has reached 10, for the record, including Huaxi Bio-technology Co.

In the field of cosmetics, NMN is mainly used as skin protection agent, moisturising agent, anti-wrinkle agent and antioxidant. At present, the domestic e-commerce platform has NMN water cream, NMN mask and other hot-selling products.

It is worth mentioning that, according to the domestic WeChat Search Volume Index, NMN's index fluctuated relatively greatly in the past year, and its search volume peaked in September 2023 and showed a larger-scale growth in March and May 2024, which indicates that NMN's heat has always existed but is not stable.

NMN becomes a potential make-up and food ingredient

In recent years, the NMN concept has been hot in China. However, the lack of efficacy verification, the development of relevant regulations and the accompanying false propaganda such as "immortality drug" have hindered the further development of NMN in the domestic food circuit. However, with China's release of NMN as a cosmetic raw material for the record application, the future of NMN in the Chinese market is expected to obtain further recognition of food regulations. Many industry insiders believe that NMN may become the next.