China is currently the world's largest producer and seller of hyaluronic acid raw materials. In 2021 , China's total sales of hyaluronic acid raw materials accounted for 82% of the global total sales . Among them, Bloomage Biotechnology Co., Ltd. (hereinafter referred to as " Bloomage Biotechnology " ) is a world-renowned hyaluronic acid raw material research and development, production and sales company, accounting for 44% of the global raw material market in 2021 .

"The reason why we initiated the Hyaluronic Acid Industry Conference is, on the one hand, because China has a say in the field of hyaluronic acid. As a backbone enterprise, Bloomage Biotechnology hopes to use this substance to drive the extension of upstream and downstream industries, trigger the consumer market's continued attention to industries related to life and health consumer products, and drive a trillion-level industry scale. On the other hand, we also hope to build a communication platform through the conference, contribute to the development of Jinan's life and health industry, and make hyaluronic acid one of Jinan's city IPs . " Zhao Yan, Chairman and President of Bloomage Biotechnology, expressed his views on related hot topics.

New quality productivity: innovation, transformation and green

Zhao Yan believes that new quality productivity must have three characteristics: first, it must be innovative in research and development; second, after innovation, it must be able to achieve industrial and market transformation and effectively improve productivity; and third, it must be environmentally friendly, green and sustainable.

As one of the representative companies in the field of biomanufacturing, Bloomage Biotechnology is exploring independent and distinctive paths in terms of empowering the industry and developing new quality productivity. On the R&D side, Bloomage Biotechnology has formed a strong R&D team of more than 900 people, and has established more than 20 innovation centers in cooperation with world-renowned scientific research institutes to solve the problem of material discovery from "0-1" ; on the industrial transformation side, Bloomage Biotechnology has built a large-scale pilot transformation platform in the world to solve the problem of industrial transformation from "1-10-100" , which is also the core key for Bloomage Biotechnology to realize industrial empowerment and connect industry, academia and research; on the market transformation side, Bloomage Biotechnology is one of the few biomanufacturing full industry chain platform companies in the world. After obtaining new scientific research results, it can quickly launch terminal products, achieve market verification, and promote industry development and standard setting.

Specifically in the industry, due to the long research and development and verification cycle of medicines, cosmetics have become the first application scenario for innovative raw materials in biomanufacturing. Zhao Yan believes that the key for Chinese cosmetics companies to build core competitiveness lies in the innovation of raw materials. Product innovation without raw materials is castles in the air. In this regard, Huaxi Bio's response strategy is to advance the layout of new substances, have its own new material map, form a differentiated system, and move forward step by step. "We want to be the pioneers of the industry. The ceiling must be high enough, the barriers must be wide enough, and the roots must be solid enough, so that we will not be easily surpassed by others." Zhao Yan said.

Synthetic biology: great potential, the main global direction in the future

"Synthetic biology", "synthetic biotechnology" and "biomanufacturing supported by synthetic biology" are three logical systems at different levels. Synthetic biology is a biotechnology that empowers the industry. The development of synthetic biology has benefited from the development of basic disciplines and interdisciplinary disciplines, such as gene detection, gene synthesis, gene editing, etc., together with the development of interdisciplinary disciplines such as bioinformatics, engineering, and AI , which have jointly promoted the development of synthetic biotechnology to today's level and become an important foundation for supporting the development of the biomanufacturing industry.

Today, changes in the global ecological environment have brought about a series of crises. To solve these problems, the support of synthetic biology is needed. Biomanufacturing supported by synthetic biology has changed the traditional ways of obtaining materials such as animal extraction, plant extraction, and chemical synthesis, and has provided support for achieving dual carbon goals and sustainable development. Zhao Yan said that the country regards biomanufacturing as a key industry for the development of new quality productivity, and it ranks at the forefront of the main front industries for promoting the development of new quality productivity. Biomanufacturing supported by synthetic biology has great potential in the future and will become the main direction and development trend of the industry in the future.

Hyaluronic acid: promoting the development of life and health

Small material, big future. The "hyaluronic acid effect" formed by the hyaluronic acid industry is driving the continuous development of the life and health field. The deeper the basic research on this industry, the wider the application field of hyaluronic acid will be. Zhao Yan said that Huaxi Bio's research on hyaluronic acid has lasted for more than 20 years. The basic research and applied basic research of hyaluronic acid, continuous in-depth research and continuous innovation are the foundation of the company's long-term vitality.

Enterprise development: adhere to synthetic biology and seize the strategic commanding heights

We must persist in synthetic biology and adhere to it, and we must keep innovating. Bloomage Bio is working hard to promote innovation and development in the field of biomanufacturing supported by synthetic biology across the industry.

Zhao Yan said: "We have made arrangements in advance, such as investing nearly 2 billion yuan to build a large pilot transformation platform in Tianjin. If we don't get through this link and do results transformation and industrial transformation, we won't be able to realize productization. This is also the core support for China's biomanufacturing to seize the strategic commanding heights. China has advantages in the fields of synthetic biology and biomanufacturing. Based on the large amount of industrialization experience, talent team and supply chain advantages we have accumulated in the field of biological fermentation, we have great potential. Bloomage will continue to invest, layout and deepen its cultivation. "